Section 1 – Chemical product identification
Product name: Sodium Chloride
TSCA: TSCA 8(b) inventory: Sodium chloride
CI#: Not applicable.
Synonym: Sea salt, salt
Chemical Name: Sodium Chloride
Chemical Formula: NaCl
Section 2: Composition and Information on Ingredients
- Sodium Chloride, CAS # 7647-14-5, 100 % by weight
Toxicological Data on Ingredient Sodium Chloride:
Acute LD50 oral:
- Rat: 3000 mg / kg
- Mouse: 4000 mg / kg
Acute LD50 dermal:
- Rabbit: > 10,000 mg/kg
Acute LC50 dust:
- Rat: > 42,000 mg/m 1 hour
Section 3: Hazards Identification
Potential Acute Health Effects: Slightly hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation.
Potential Chronic Health Effects:
- CARCINOGENIC EFFECTS: None.
- MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells. Mutagenic for bacteria and/or yeast.
- TERATOGENIC EFFECTS: None.
- DEVELOPMENTAL TOXICITY: None.
- Repeated or prolonged exposure is not known to aggravate medical condition.
Section 4: First Aid Measures
Eye Contact: Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15
minutes. Cold water may be used. Get medical attention.
Skin Contact: Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops. Cold water may be used.
Serious skin contact: Not applicable.
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical
attention if symptoms appear.
Serious inhalation: Not applicable.
Ingestion: Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention if symptoms appear.
Serious ingestion: Not applicable.
Section 5: Fire and Explosion Data
Flammability of the Product: Non-flammable.
Auto-Ignition Temperature: Not applicable.
Flash Points: Not applicable.
Flammable Limits: Not applicable.
Products of Combustion: Not available.
Fire Hazards in Presence of Various Substances: Not applicable.
Explosion Hazards in Presence of Various Substances: Not applicable.
Risks of explosion of the product in presence of mechanical impact: Not available.
Risks of explosion of the product in presence of static discharge: Not available.
Fire Fighting Media and Instructions: Not applicable.
Special Remarks on Fire Hazards: When heated to decomposition it emits toxic fumes.
Special Remarks on Explosion Hazards: Electrolysis of sodium chloride in presence of nitrogenous compounds to produce chlorine may lead to formation of explosive nitrogen trichloride. Potentially explosive reaction with dichloromaleic anhydride + urea.
Section 6: Accidental Release Measures
Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on
the contaminated surface and dispose of according to local and regional authority requirements.
Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the
contaminated surface and allow to evacuate through the sanitary system
Section 7: Handling and Storage
Keep locked up.. Do not ingest. Do not breathe dust. Avoid contact with eyes. Wear suitable protective clothing. If ingested, seek medical advice immediately and show the container or the label. Keep away from incompatibles such as oxidizing agents, acids.
Keep container tightly closed. Keep container in a cool, well-ventilated area. Hygroscopic
Section 8: Exposure Controls/Personal Protection
Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit.
Splash goggles. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.
Personal Protection in Case of a Large Spill:
Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product.
Exposure Limits: Not available.
Section 9: Physical and Chemical Properties
Physical state and appearance: Solid. (Solid crystalline powder.)
Molecular Weight: 58.44 g/mole
pH (1% soln/water): 7 [Neutral.]
Boiling Point: 1413°C (2575.4°F)
Melting Point: 801°C (1473.8°F)
Critical Temperature: Not available.
Specific Gravity: 2.165 (Water = 1)
Vapor Pressure: Not applicable.
Vapor Density: Not available.
Volatility: Not available.
Odor Threshold: Not available.
Water/Oil Dist. Coeff.: Not available.
Ionicity (in Water): Not available.
Dispersion Properties: See solubility in water.
Solubility: Easily soluble in cold water, hot water. Soluble in glycerol, and ammonia. Very slightly soluble in alcohol. Insoluble in Hydrochloric Acid.
Section 10: Stability and Reactivity Data
Stability: The product is stable.
Instability Temperature: Not available.
Conditions of Instability: Incompatible materials, high temperatures.
Incompatibility with various substances: Reactive with oxidizing agents, metals, acids.
Corrosivity: Not considered to be corrosive for metals and glass.
Special Remarks on Reactivity: Hygroscopic. Reacts with most nonnoble metals such as iron or steel, building materials (such as cement) Sodium chloride is rapidly attacked by bromine trifluoride. Violent reaction with lithium.
Special Remarks on Corrosivity: Not available.
Polymerization: Will not occur.
Section 11: Toxicological Information
Routes of Entry: Inhalation, ingestion.
Toxicity to Animals:
WARNING: THE LC50 VALUES HEREUNDER ARE ESTIMATED ON THE BASIS OF A 4-HOUR EXPOSURE.
- Acute oral toxicity (LD50): 3000 mg/kg [Rat.].
- Acute dermal toxicity (LD50): >10000 mg/kg [Rabbit].
- Acute toxicity of the dust (LC50): >42000 mg/m3 1 hours [Rat].
Chronic Effects on Humans:
- MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells. Mutagenic for bacteria and/or yeast.
Other Toxic Effects on Humans: Slightly hazardous in case of skin contact (irritant), of ingestion, of inhalation.
Special Remarks on Toxicity to Animals: Lowest Published Lethal Dose (LDL) [Man] – Route: Oral; Dose: 1000 mg/kg
Special Remarks on Chronic Effects on Humans: Causes adverse reproductive effects in humans (fetotoxicity, abortion, ) by intraplacental route. High intake of sodium chloride,
whether from occupational exposure or in the diet, may increase risk of TOXEMIA OF PREGNANCY in susceptible women (Bishop, 1978). Hypertonic sodium chloride solutions have been used to induce abortion in late pregnancy by direct infusion into the uterus (Brown et al, 1972), but this route of administration is not relevant to occupational exposures. May cause
adverse reproductive effects and birth defects in animals, particularly rats and mice (fetotoxicity, abortion, musculoskeletal abnormalities, and maternal effects (effects on ovaries, fallopian tubes) by oral, intraperitoneal, intraplacental, intrauterine, parenteral, and subcutaneous routes. While sodium chloride has been used as a negative control n some reproductive
studies, it has also been used as an example that almost any chemical can cause birth defects in experimental animals if studied under the right conditions (Nishimura & Miyamoto, 1969). In experimental animals, sodium chloride has caused delayed effects on newborns, has been fetotoxic, and has caused birth defects and abortions in rats and mice (RTECS, 1997). May affect genetic material (mutagenic)
Special Remarks on other Toxic Effects on Humans: Acute Potential Health Effects: Skin: May cause skin irritation. Eyes: Causes eye irritation. Ingestion: Ingestion of large
quantities can irritate the stomach (as in overuse of salt tablets) with nausea and vomiting. May affect behavior (muscle spasicity/contraction, somnolence), sense organs, metabolism, and cardiovascular system. Continued exposure may produce dehydration, internal organ congestion, and coma. Inhalation: Material is irritating to mucous membranes and upper respiratory tract.
Section 12: Ecological Information
Ecotoxicity: Not available.
BOD5 and COD: Not available.
Products of Biodegradation:
Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise.
Toxicity of the Products of Biodegradation: The product itself and its products of degradation are not toxic.
Special Remarks on the Products of Biodegradation: Not available.
Section 13: Disposal Considerations
Waste Disposal: Waste must be disposed of in accordance with federal, state and local environmental control regulations.
Section 14: Transport Information
DOT Classification: Not a DOT controlled material (United States).
Identification: Not applicable.
Special Provisions for Transport: Not applicable.
Section 15: Other Regulatory Information
Federal and State Regulations: TSCA 8(b) inventory: Sodium chloride
Other Regulations: EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances.
WHMIS (Canada): Not controlled under WHMIS (Canada).
R40- Possible risks of irreversible effects. S24/25- Avoid contact with skin and eyes.
Health Hazard: 1
Fire Hazard: 0
Personal Protection: E
National Fire Protection Association (U.S.A.):
Protective Equipment: Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Splash goggles.
Section 16: Other Information
References: -Hawley, G.G.. The Condensed Chemical Dictionary, 11e ed., New York N.Y., Van Nostrand Reinold, 1987. -SAX, N.I.
Dangerous Properties of Indutrial Materials. Toronto, Van Nostrand Reinold, 6e ed. 1984. -The Sigma-Aldrich Library of Chemical Safety Data, Edition II.
Other Special Considerations: Not available.